Curazelic 44

Documented efficacy

Azelaic acid has numerous pharmacological and cosmetic uses.

Its anti-inflammatory and anti-oxidant properties are thought to correlate with its efficacy in rosacea and acne.

Reduction in erythema as well as skin brightening has also been documented

Growing body of publication documenting its efficacy

Improved acne treatments

Work alongside approved acne ingredients to helps troubled skin

Helps reduce the expression of inflammatory-markers triggered by traditional anti-acne ingredients

Azelaic acid (AA) is a dicarboxylic acid found naturally. It is even produced by commensal fungi found on the skin (Malassesia). It can also be produced from oleic acid extracted from vegetable oils. Pure azelaic acid is a white crystalline solid.

Several studies have demonstrated the versatility of azelaic acid in helping address a broad array of skin disorders.

Azelaic acid has numerous pharmacological and cosmetic uses:

Its anti-inflammatory and anti-oxidant properties are thought to correlate with its efficacy in rosacea and acne.

Topical drugs containing 20% of dispersed azelaic acid are approved by the FDA for the treatment of acne vulgaris.

Topical drugs containing 15% of dispersed azelaic acid are approved by the FDA for the treatment rosacea.

In cosmetics applications, azelaic acid used at 10% or less is used to help reduce the appearance of skin blemishes, brighten skin tones and even out complexion.

Studies also suggest azelaic acid could benefit people suffering from early hair loss

Compatibility:

With cosmetic oils, waxes, and cationic and non-ionic emulsifiers.

With polyols and PEGs.

With cationic, amphoteric, and non-ionic surfactants.

With most water-soluble ingredients that are not pH sensitive.

With cationic and non-ionic thickeners.

With low concentrations of anionic surfactants and select thickeners at pH above 5.0.

Incompatibility:

With anionic surfactants and thickeners at pH below 4.5.

With most grades of carbomer and sodium polyacrylate.

Recommended use level and pH

As an acid in skin care formulations:

11.4% to 22.8% CURAZELIC® 44 for 5% to 10% active azelaic acid

pH range: 5.0 to 6.5