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RAW MATERIALS COSMETICS
- Massage Tools
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- Antiageing – Antiwrinkies
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PACKAGING
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INSTRUMENTS & LABORATORY
- Plastic Beakers
- Beakers with handle graduated
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- Petri Dishes Plastic
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- Plastic Bottles
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OENOLOGICAL & FOOD
- BLOG
INCI Name: Acetyl Hexapeptide-1
Laugh, cry, enjoy and be free to live. Do not let fine lines #chooseyourexpression. Munapsys™ is a botulinum toxin-like peptide obtained by in silico design in collaboration with experts in neuroscience.
It is the first cosmetic ingredient able to act both in the pre- and post-synaptic pathways of muscle contraction and in a new SNARE protein (Munc-18). Munc-18 binds to syntaxin allowing the assembly of the SNARE complex. Pre-synaptic: Munapsys™ competes with Munc-18 for its position in syntaxin, obstructing SNARE complex assembly and the release of the acetylcholine (ACh) neurotransmitter into the synapse. Post-synaptic: ACh activates clustered AChR, inducing a depolarization and opening Ca2+ channels allowing actomyosin cross-bridge and sliding for muscle contraction. Munapsys™ modulates AChR clustering, depolarization, Ca2+ mobilization, and actomyosin cross-bridge and sliding.
Munapsys™ mechanism is a real upgrade in the expression lines field, with proven efficacy compared with a benchmark combination even at a lower dose. Let yourself enjoy from a new generation of botulinum-like ingredients. A safe, real beauty filter.
Munapsys
INCI Name: Acetyl Hexapeptide-1
Laugh, cry, enjoy and be free to live. Do not let fine lines #chooseyourexpression. Munapsys™ is a botulinum toxin-like peptide obtained by in silico design in collaboration with experts in neuroscience.
It is the first cosmetic ingredient able to act both in the pre- and post-synaptic pathways of muscle contraction and in a new SNARE protein (Munc-18). Munc-18 binds to syntaxin allowing the assembly of the SNARE complex. Pre-synaptic: Munapsys™ competes with Munc-18 for its position in syntaxin, obstructing SNARE complex assembly and the release of the acetylcholine (ACh) neurotransmitter into the synapse. Post-synaptic: ACh activates clustered AChR, inducing a depolarization and opening Ca2+ channels allowing actomyosin cross-bridge and sliding for muscle contraction. Munapsys™ modulates AChR clustering, depolarization, Ca2+ mobilization, and actomyosin cross-bridge and sliding.
Munapsys™ mechanism is a real upgrade in the expression lines field, with proven efficacy compared with a benchmark combination even at a lower dose. Let yourself enjoy from a new generation of botulinum-like ingredients. A safe, real beauty filter.
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