Lakesis Oil
INCI name: Caprylic/capric triglyceride (and) Pistacia Lentiscus (Mastic) Gum
Recommended % of use: 0.2%
LAKESIS is an oil obtained by supercritical CO2 extraction from crystal drops collected on Pistacia lentiscus, a tree which is native to the Island of Chios (Greece).
The resinous sap produced by this tree forms drops as it falls to the ground. Once solidified, these drops take on a crystalline shape and are known as “crystal tears”.
The name of the oil obtained from these crystals is LAKESIS and refers to the Greek legend of the Three Fates.
The Precious Oil of Crystal Tears increases the synthesis of Klotho protein in the fibroblasts. In reference to the legend, we have called this oil Lakesis, from the name of the second goddess who measures lifespan.
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YOUTH PROTEINS
Studied very thoroughly during the past few years, FOXO has being considered to be the youth protein.
Its role in cellular protection and longevity has been well described and targeted to combat aging.
Located directly inside the nucleus, the “nuclear” form of FOXO activates the transcription of genes involved in cellular detoxification and the repair of DNA damages
THE NEW youth protein: KLOTHO
A protein which is able to inhibit AKT activation and therefore maintain FOXO inside the cell nucleus was identified in 2005.
Named KLOTHO in reference to the Greek goddess Clotho, who spins the thread of life, it is now considered by scientists to be the NEW YOUTH PROTEIN.
The decrease in KLOTHO expression starts very early during the ageing process: from roughly 30 years. Then its expression gradually decreases with fibroblasts ageing.
Increasing Klotho synthesis in the fibroblasts thus represents a new strategy to combat skin aging.
IN VITRO:
Increases synthesis of the KLOTHO youth protein
Increases the level of the FOXO youth protein
Reactivates the cellular detoxification process
Reactivates cellular activity
Promotes redensification of dermal matrix
IN VIVO:
Improves density of the SENEB and decreases its surface
Increases supporting fiber density in the dermis and ensures homogeneous fibers distribution
Lifts the facial contours
Skin appears younger
Skin seems thicker and firmer
EXAMPLES OF USE
In an anti-aging facial oil
In a global anti-aging product
In a youth-reactivating serum
In a youth-detoxifying night cream
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